Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 3/20 | 0.38 |
| ▸ | CDK8 | P49336 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27114140 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2TBXAS1GAA | |
| SCHEMBL27114135 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2TBXAS1GAA | |
| SCHEMBL24408970 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL27114062 | 0.82 | TBXAS1 (0.43) | KDM4EALDH1A1SMN1; SMN2TBXAS1GAA | |
| SCHEMBL24408993 | 0.82 | CXCR1 (0.42) | KDM4EALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL24409081 | 0.82 | MAPT (0.44) | KDM4EALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL24419697 | 0.81 | POLB (0.47) | KDM4EALDH1A1SMN1; SMN2TBXAS1HSD17B10 | |
| SCHEMBL27114084 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2TBXAS1GAA | |
| SCHEMBL27114065 | 0.80 | TBXAS1 (0.41) | KDM4EALDH1A1SMN1; SMN2TBXAS1GAA | |
| SCHEMBL24425000 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1SMN1; SMN2GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096445-A1 | [(1-PHENYL-5-HETEROARYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | WO | disclosed |