SCHEMBL24419897

SCHEMBL24419897

C[C@@H](O)[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.43
▸ NPY1R P25929 9/20 0.43
▸ NPY5R Q15761 8/20 0.43
▸ NPY2R P49146 5/20 0.43
▸ SIRT2 Q8IXJ6 1/20 0.37
▸ SIRT5 Q9NXA8 1/20 0.37
▸ PDCD1LG2 Q9BQ51 1/20 0.37
▸ CD274 Q9NZQ7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30658141 0.94 NPY4R (0.42) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30685283 0.91 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30658148 0.91 ENPEP (0.42) NPY4RNPY1RNPY5RNPY2R
SCHEMBL32679342 0.91 NPY4R (0.40) NPY4RNPY1RNPY5RNPY2RSIRT2
SCHEMBL29540572 0.91 NPY4R (0.39) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31265325 0.89 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RSIRT5
SCHEMBL29697049 0.89 NPY4R (0.41) NPY4RNPY1RNPY5RNPY2R
SCHEMBL9819648 0.89 NPY4R (0.41) NPY4RNPY1RNPY5RNPY2R
SCHEMBL9819642 0.89 NPY4R (0.41) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29784994 0.87 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12543727-B2 Thawing fluid, preparation method therefor and use thereof PEKING UNIVERSITY THIRD HOSPITAL (CN) 2026-02-10 — — US claimed
US-12408659-B2 DMSO-free cryopreservation solution and preparation method and use thereof PEKING UNIVERSITY THIRD HOSPITAL (CN) 2025-09-09 — — US claimed
CN-118979012-A Thawing liquid for ovum or embryo and preparation method and thawing method thereof 上海北里永幸医疗器械有限公司 2024-11-19 — — CN claimed
CN-111793110-B Application of DMSO-free cryopreservation liquid in stem cell cryopreservation 北京大学第三医院(北京大学第三临床医学院) 2022-11-11 — — CN claimed
CN-111789100-B Application of DMSO-free cryopreservation solution in cryopreservation of oocytes or embryos 北京大学第三医院 2022-09-06 — — CN claimed
CN-111789099-B Application of cryopreservation liquid containing peptide compounds in cryopreservation of oocytes or embryos 北京大学第三医院 2022-09-06 — — CN claimed
CN-111789102-B Application of thawing solution in thawing frozen and preserved oocyte or embryo 北京大学第三医院 2022-07-12 — — CN claimed
US-20220192180-A1 THAWING FLUID, PREPARATION METHOD THEREFOR AND USE THEREOF PEKING UNIVERSITY THIRD HOSPITAL (CN) 2022-06-23 — — US claimed
US-20220167610-A1 DMSO-FREE CRYOPRESERVATION SOLUTION AND PREPARATION METHOD AND USE THEREOF PEKING UNIVERSITY THIRD HOSPITAL (CN) 2022-06-02 — — US claimed
CN-111793108-B Application of cryopreservation liquid containing peptide compounds in organ and tissue cryopreservation 北京大学第三医院(北京大学第三临床医学院) 2022-05-27 — — CN claimed
CN-111793109-B Peptide compound and cryopreservation liquid containing same 中国科学院化学研究所 2022-05-27 — — CN claimed
CN-111789103-B Thawing solution for cryopreservation and thawing method 中国科学院化学研究所 2022-05-27 — — CN claimed
US-20220142148-A1 SERUM-FREE CRYOPRESERVATION SOLUTION AND PREPARATION METHOD AND APPLICATION THEREOF INSTITUTE OF CHEMISTRY, CHINESE ACADEMIC OF SCIENCES (CN) 2022-05-12 — — US claimed
CN-111793107-B DMSO-free cryopreservation liquid and preparation method thereof 中国科学院化学研究所 2022-04-12 — — CN claimed
US-12543727-B2 Thawing fluid, preparation method therefor and use thereof PEKING UNIVERSITY THIRD HOSPITAL (CN) 2026-02-10 — — US disclosed
US-12453345-B2 Serum-free cryopreservation solution and preparation method and application thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMIC OF SCIENCES (CN) 2025-10-28 — — US disclosed
US-12408659-B2 DMSO-free cryopreservation solution and preparation method and use thereof PEKING UNIVERSITY THIRD HOSPITAL (CN) 2025-09-09 — — US disclosed
US-20220142148-A1 SERUM-FREE CRYOPRESERVATION SOLUTION AND PREPARATION METHOD AND APPLICATION THEREOF INSTITUTE OF CHEMISTRY, CHINESE ACADEMIC OF SCIENCES (CN) 2022-05-12 — — US disclosed
CN-111793107-B DMSO-free cryopreservation liquid and preparation method thereof 中国科学院化学研究所 2022-04-12 — — CN disclosed
CN-111790327-B Molecular design method of ice control material 中国科学院化学研究所 2022-03-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12543727-B2 Thawing fluid, preparation method therefor and use thereof PCMT1, ARGLU1, TTR NPY4R 3235/4885NPY1R 2711/4885NPY5R 3579/4885
US-20220142148-A1 SERUM-FREE CRYOPRESERVATION SOLUTION AND PREPARATION METHOD AND APPLICATION THEREOF BCL2L1, BCL2, BCL2L11 NPY4R 4591/4885NPY1R 4003/4885NPY5R 4470/4885
US-12408659-B2 DMSO-free cryopreservation solution and preparation method and use thereof BCL2, BCL2L1, BCL2L2 NPY4R 4809/4885NPY1R 4266/4885NPY5R 4740/4885
US-12453345-B2 Serum-free cryopreservation solution and preparation method and application thereof BCL2L1, BCL2, BCL2L11 NPY4R 4591/4885NPY1R 4003/4885NPY5R 4470/4885
US-20220167610-A1 DMSO-FREE CRYOPRESERVATION SOLUTION AND PREPARATION METHOD AND USE THEREOF BCL2, BCL2L1, BCL2L2 NPY4R 4809/4885NPY1R 4266/4885NPY5R 4740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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