Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 9/20 | 0.52 |
| ▸ | TK1 | P04183 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TYMP | P19971 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15110503 | 0.86 | TK2 (0.60) | TK2TK1MAPK1TYMPHPGD | |
| SCHEMBL16260043 | 0.81 | MAPK1 (0.54) | TK2TK1MAPK1TYMPHPGD | |
| SCHEMBL26779948 | 0.81 | TK1 (0.60) | TK2TK1MAPK1TYMPHPGD | |
| SCHEMBL7124047 | 0.80 | HPGD (0.55) | TK2TK1MAPK1TYMPHPGD | |
| SCHEMBL20743084 | 0.80 | TK2 (0.55) | TK2TK1MAPK1TYMPHPGD | |
| SCHEMBL5025559 | 0.80 | TK2 (0.55) | TK2TK1MAPK1TYMPHPGD | |
| SCHEMBL2496425 | 0.80 | HPGD (0.55) | TK2TK1MAPK1TYMPHPGD | |
| SCHEMBL8301264 | 0.80 | TYMP (0.56) | TK2TK1MAPK1TYMPHPGD | |
| SCHEMBL5025556 | 0.80 | TK2 (0.55) | TK2TK1MAPK1TYMPHPGD | |
| SCHEMBL20012371 | 0.80 | TK2 (0.55) | TK2TK1MAPK1TYMPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |