SCHEMBL24420699

SCHEMBL24420699

CC(C)(C)[Si](C)(C)OC[C@H]1OC=C[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.33
TOP2A P11388 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22639184 1.00 DUT (0.33) DUTTOP2A
SCHEMBL22639340 1.00 DUT (0.33) DUTTOP2A
SCHEMBL14255134 0.89 DUT (0.31) DUT
SCHEMBL14255133 0.89 DUT (0.31) DUT
SCHEMBL8068702 0.89 DUT (0.31) DUT
SCHEMBL9632845 0.89 DUT (0.31) DUT
SCHEMBL20225134 0.89 DUT (0.31) DUT
SCHEMBL6857582 0.83 CYP3A4 (0.33) DUT
SCHEMBL6271581 0.78
SCHEMBL1578986 0.77 FUCA1 (0.41) DUTTOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250303002-A1 PYRIMIDINE NUCLEOSIDE COMPOUNDS FOR FLUORESCENCE IMAGING AND SPECTROSCOPY San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation (US) 2025-10-02 US disclosed
US-12329828-B2 Pyrimidine nucleoside compounds for fluorescence imaging and spectroscopy SAN DIEGO STATE UNIVERSITY (SDSU) FOUNDATION (US) 2025-06-17 US disclosed
EP-4404942-A2 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2024-07-31 EP disclosed
US-20240026358-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2024-01-25 US disclosed
US-20240026358-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2024-01-25 US disclosed
WO-2023220428-A1 COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 WO disclosed
EP-4240849-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2023-09-13 EP disclosed
CN-116507724-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2023-07-28 CN disclosed
WO-2023049477-A2 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-03-30 WO disclosed
WO-2022099159-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2022-05-12 WO disclosed
US-20220088226-A1 PYRIMIDINE NUCLEOSIDE COMPOUNDS FOR FLUORESCENCE IMAGING AND SPECTROSCOPY SAN DIEGO STATE UNIVERSITY FOUNDATION (US) 2022-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220088226-A1 PYRIMIDINE NUCLEOSIDE COMPOUNDS FOR FLUORESCENCE IMAGING AND SPECTROSCOPY DNA2, SLC29A2, PCNA DUT 14/4885TOP2A 47/4885
US-12329828-B2 Pyrimidine nucleoside compounds for fluorescence imaging and spectroscopy DNA2, SLC29A2, PCNA DUT 14/4885TOP2A 47/4885
US-20250303002-A1 PYRIMIDINE NUCLEOSIDE COMPOUNDS FOR FLUORESCENCE IMAGING AND SPECTROSCOPY DNA2, SLC29A2, PCNA DUT 14/4885TOP2A 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.