SCHEMBL8068702

SCHEMBL8068702

CC(C)(C)[Si](C)(C)OC[C@H]1OC=C[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9632845 1.00 DUT (0.31) DUT
SCHEMBL24420699 0.89 DUT (0.33) DUT
SCHEMBL22639184 0.89 DUT (0.33) DUT
SCHEMBL22639340 0.89 DUT (0.33) DUT
SCHEMBL6857582 0.88 CYP3A4 (0.33) DUT
SCHEMBL20225134 0.85 DUT (0.31) DUT
SCHEMBL14255134 0.85 DUT (0.31) DUT
SCHEMBL14255133 0.85 DUT (0.31) DUT
SCHEMBL9092675 0.78 MAPT (0.36) DUT
SCHEMBL18639237 0.76 GBA1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3313200-B1 (5R)-(SS-D-GLUCOPYRANOSYLOXY)-1,5-DIHYDRO-2H-PYRROL-2-ONE AS UMAMI MOLECULE NESTEC SA (CH) 2019-04-03 EP disclosed
US-20180153203-A1 (5R)-(ß-D-GLUCOPYRANOSYLOXY)-1,5-DIHYDRO-2H-PYRROL-2-ONE AS UMAMI MOLECULE Société des Produits Nestlé S.A. (CH) 2018-06-07 US disclosed
EP-3313200-A1 (5R)-(ß-D-GLUCOPYRANOSYLOXY)-1,5-DIHYDRO-2H Nestec S.A. (CH) 2018-05-02 EP disclosed
WO-2016207174-A1 (5R)-(ß-D-GLUCOPYRANOSYLOXY)-1,5-DIHYDRO-2H-PYRROL-2- ONE AS UMAMI MOLECULE NESTEC S.A. (CH) 2016-12-29 WO disclosed
US-6080771-A LEINAMYCIN DERIVATIVES ARE USED AS BACTERICIDE AND ANTITUMOR AGENTS KYOWA HAKKO KOGYO CO., LTD. (JP) 2000-06-27 US disclosed
EP-0887351-A1 DC 107 DERIVATIVES (2) KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-12-30 EP disclosed