Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.43 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ME2 | P23368 | 3/20 | 0.38 |
| ▸ | ME1 | P48163 | 3/20 | 0.38 |
| ▸ | ME3 | Q16798 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | SORD | Q00796 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21934609 | 0.85 | CYP11B1 (0.41) | SMOAOC3PANK3CYP11B1CYP11B2 | |
| SCHEMBL11988947 | 0.83 | SMO (0.52) | SMOHRH3AOC3SMN1; SMN2HTR1A | |
| SCHEMBL3980082 | 0.82 | AOC3 (0.46) | SMOAOC3PANK3CYP11B1CYP11B2 | |
| SCHEMBL3086082 | 0.80 | AOC3 (0.54) | SMOHRH3AOC3JAK2JAK1 | |
| SCHEMBL844082 | 0.80 | GAA (0.52) | SMOHRH3AOC3CYP11B1CYP11B2 | |
| SCHEMBL29562890 | 0.80 | AOC3 (0.47) | AOC3PANK3ME2ME1ME3 | |
| SCHEMBL24422287 | 0.80 | ME2 (0.52) | SMOME2ME1ME3SMN1; SMN2 | |
| SCHEMBL987818 | 0.79 | AOC3 (0.55) | SMOHRH3AOC3HPGDALDH1A1 | |
| SCHEMBL24421697 | 0.79 | HRH3 (0.65) | SMOHRH3ALDH1A1MAPT | |
| SCHEMBL19001112 | 0.78 | OGA (0.54) | SMOHRH3HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144838-A1 | Compounds as Inhibitors of Macrophage Migration Inhibitory Factor | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144838-A1 | Compounds as Inhibitors of Macrophage Migration Inhibitory Factor | MIF, MMP12, SLC11A2 | SMO 3225/4885HRH3 2018/4885AOC3 2264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.