Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27386125 | 0.91 | TSHR (0.44) | ACE2PTPN1MAPTLMNASPHK2 | |
| SCHEMBL19466238 | 0.86 | ACE2 (0.52) | ACE2LMNAALDH1A1SPHK2SPHK1 | |
| SCHEMBL21779188 | 0.84 | NFKB1 (0.47) | ALDH1A1SPHK2SPHK1DNM1FDPS | |
| SCHEMBL20228810 | 0.83 | PTPN1 (0.35) | PTPN1LMNATSHR | |
| SCHEMBL28154748 | 0.83 | ACE2 (0.42) | ACE2PTPN1MAPTLMNAALDH1A1 | |
| SCHEMBL19301770 | 0.81 | LMNA (0.59) | PTPN1LMNA | |
| SCHEMBL18514502 | 0.81 | ACE2 (0.36) | ACE2ALDH1A1SPHK2SPHK1DNM1 | |
| SCHEMBL1781778 | 0.79 | ACE2 (0.48) | ACE2PTPN1MAPTALDH1A1CA2 | |
| SCHEMBL11638149 | 0.79 | — | — | |
| SCHEMBL56652 | 0.79 | LMNA (0.50) | ACE2MAPTLMNAALDH1A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |