Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24422996 | 1.00 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL24423311 | 1.00 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL4895658 | 0.74 | CASR (0.36) | HTR2CHTR2B | |
| SCHEMBL24423000 | 0.71 | BRD4 (0.37) | — | |
| SCHEMBL24423005 | 0.71 | BRD4 (0.37) | — | |
| SCHEMBL24422994 | 0.71 | BRD4 (0.37) | — | |
| SCHEMBL16077533 | 0.70 | RET (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL24422443 | 0.69 | NOS1 (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL24422998 | 0.69 | NOS1 (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL24422440 | 0.69 | NOS1 (0.35) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022098992-A1 | USE OF MACROCYCLIC COMPOUNDS IN METHODS OF TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |