Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24423000 | 1.00 | BRD4 (0.37) | BRD4GSK3BLMNAGAAMEN1 | |
| SCHEMBL24422994 | 1.00 | BRD4 (0.37) | BRD4GSK3BLMNAGAAMEN1 | |
| SCHEMBL24423438 | 0.81 | MEN1 (0.34) | BRD4GSK3BMEN1KMT2A | |
| SCHEMBL15596523 | 0.74 | GSK3B (0.44) | BRD4GSK3BLMNAGAAMEN1 | |
| SCHEMBL4898103 | 0.74 | BRD4 (0.41) | BRD4LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL10358533 | 0.74 | BRD4 (0.41) | BRD4LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL27051279 | 0.72 | ADRB1 (0.36) | LMNAALDH1A1 | |
| SCHEMBL24422996 | 0.71 | HTR2A (0.33) | — | |
| SCHEMBL24422993 | 0.71 | HTR2A (0.33) | — | |
| SCHEMBL24423311 | 0.71 | HTR2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022098992-A1 | USE OF MACROCYCLIC COMPOUNDS IN METHODS OF TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |