Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496435 | 0.82 | — | — | |
| SCHEMBL15967598 | 0.73 | KMT2A (0.37) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28508385 | 0.73 | — | — | |
| SCHEMBL11198457 | 0.72 | — | — | |
| SCHEMBL22228986 | 0.72 | — | — | |
| SCHEMBL12312029 | 0.71 | KMT2A (0.37) | KMT2AALDH1A1POLBLMNAMAPK1 | |
| SCHEMBL18789283 | 0.71 | ALDH1A1 (0.43) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7069432 | 0.70 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL24580648 | 0.69 | ALDH1A1 (0.42) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12000009 | 0.68 | KMT2A (0.39) | KMT2AALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |