Methacrylic Acid

Methacrylic Acid

SCHEMBL2442390

C=C(C)C(=O)O.CC=C(CCCCCCCC)OCC

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.45
FAAH O00519 2/20 0.43
THRB P10828 1/20 0.42
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
PGGT1B P53609 1/20 0.42
GPR84 Q9NQS5 7/20 0.41
PPARG P37231 7/20 0.41
PPARD Q03181 7/20 0.41
PPARA Q07869 7/20 0.41
HDAC11 Q96DB2 5/20 0.41
PTPN1 P18031 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TLR2 O60603 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FABP4 P15090 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
MEN1 O00255 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8069698 0.84 FAAH (0.46) TSHRFAAHGPR84PPARGPPARD
Methacrylic Acid SCHEMBL27685560 0.80 DGKA (0.55) TSHRALDH1A1MEN1KMT2APAM
Methacrylic Acid SCHEMBL11252010 0.79 TSHR (0.50) TSHRFAAHTHRBFNTAFNTB
SCHEMBL17355050 0.76 FAAH (0.36) TSHRFAAHALDH1A1HSD17B10
Methacrylic Acid SCHEMBL8469735 0.76 TSHR (0.56) TSHRTHRBFNTAFNTBPGGT1B
Decane SCHEMBL2509675 0.76 TSHR (0.56) TSHRTHRBFNTAFNTBPGGT1B
Dodecane SCHEMBL17222843 0.76 TSHR (0.56) TSHRTHRBFNTAFNTBPGGT1B
Octane SCHEMBL2702853 0.76 TSHR (0.56) TSHRTHRBFNTAFNTBPGGT1B
Decane SCHEMBL20943079 0.76 TSHR (0.56) TSHRTHRBFNTAFNTBPGGT1B
Tetradecane SCHEMBL16895021 0.76 TSHR (0.56) TSHRTHRBFNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2098192-B1 MULTIFOCAL EYE LENS HOYA CORP (JP) 2022-02-09 EP disclosed
EP-2375276-B1 DIFFRACTIVE MULTIFOCAL LENS HOYA CORP (JP) 2016-05-25 EP disclosed
US-8556416-B2 Diffractive multifocal lens HOYA CORPORATION (JP) 2013-10-15 US disclosed
US-20110234974-A1 Diffractive Multifocal Lens HOYA Medical Singapore Pte. Ltd. (SG) 2011-09-29 US disclosed
US-20100321632-A1 MULTIFOCAL OPHTHALMIC LENS HOYA Medical Singapore Pte. Ltd. (SG) 2010-12-23 US disclosed
EP-2098192-A1 MULTIFOCAL EYE LENS Hoya Corporation (JP) 2009-09-09 EP disclosed