Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782553 | 0.81 | ATR (0.47) | L3MBTL1LMNAKDM4ENAMPTKDM4A | |
| SCHEMBL18764702 | 0.76 | NAMPT (0.46) | L3MBTL1LMNAKDM4ENAMPTKDM4A | |
| SCHEMBL20839513 | 0.76 | ATR (0.42) | LMNANAMPTPOLBCA1CA2 | |
| SCHEMBL30890544 | 0.74 | CHRM2 (0.47) | L3MBTL1KDM4ENAMPTKDM4AMAPKAPK2 | |
| SCHEMBL1631864 | 0.74 | ADORA2A (0.48) | L3MBTL1NAMPTKDM4ASSTR4 | |
| SCHEMBL31438501 | 0.74 | L3MBTL1 (0.41) | CACNA1HCACNA1BCACNA1CL3MBTL1LMNA | |
| SCHEMBL21455353 | 0.74 | ATR (0.44) | L3MBTL1LMNANAMPTKDM4AMAPKAPK2 | |
| SCHEMBL30564617 | 0.74 | L3MBTL1 (0.41) | CACNA1HCACNA1BCACNA1CL3MBTL1LMNA | |
| SCHEMBL20520904 | 0.73 | CACNA1H (0.45) | CACNA1HCACNA1BCACNA1CL3MBTL1LMNA | |
| SCHEMBL1631862 | 0.73 | NAMPT (0.46) | L3MBTL1LMNAKDM4ENAMPTKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230062861-A1 | PPARg MODULATORS AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-03-02 | — | — | US | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062861-A1 | PPARg MODULATORS AND METHODS OF USE | PPARG, PPARA, PPARD | CACNA1H 3436/4885CACNA1B 2947/4885CACNA1C 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.