Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30564617 | 1.00 | L3MBTL1 (0.41) | L3MBTL1SSTR4NAMPTKDM4AATR | |
| SCHEMBL21455353 | 0.84 | ATR (0.44) | L3MBTL1SSTR4NAMPTKDM4AATR | |
| SCHEMBL17785366 | 0.83 | KLKB1 (0.43) | L3MBTL1SSTR4NAMPTKDM4AATR | |
| SCHEMBL29366380 | 0.83 | KLKB1 (0.43) | L3MBTL1SSTR4NAMPTKDM4AATR | |
| SCHEMBL25198671 | 0.82 | ATR (0.43) | L3MBTL1SSTR4NAMPTKDM4AATR | |
| SCHEMBL31571144 | 0.80 | NPSR1 (0.40) | L3MBTL1POLB | |
| SCHEMBL31352678 | 0.80 | SSTR4 (0.44) | L3MBTL1SSTR4NAMPTKDM4AATR | |
| SCHEMBL29023442 | 0.80 | ATR (0.41) | L3MBTL1SSTR4NAMPTKDM4AATR | |
| SCHEMBL25199363 | 0.79 | HSD17B10 (0.36) | KDM4E | |
| SCHEMBL18764702 | 0.78 | NAMPT (0.46) | L3MBTL1NAMPTKDM4AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134035-B | 3- (1H-imidazol-2-yl) -2,3,8 a-tetrahydroindol-5 (1H) -one derivatives useful as factor XIA inhibitors | 詹森药业有限公司 | 2025-03-11 | — | — | CN | disclosed |