Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29586649 | 0.98 | JAK3 (0.33) | JAK3CNR2ACACBDGAT2NPC1 | |
| SCHEMBL24423119 | 0.86 | FFAR4 (0.37) | CNR2ACACBSCDSCD5MC4R | |
| SCHEMBL29585889 | 0.86 | FFAR4 (0.37) | CNR2ACACBSCDSCD5MC4R | |
| SCHEMBL24424425 | 0.84 | NPC1 (0.42) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL24423900 | 0.82 | SMO (0.34) | SMO | |
| SCHEMBL29585529 | 0.82 | SMO (0.34) | SMO | |
| SCHEMBL24424639 | 0.79 | ACACB (0.37) | ACACBDGAT2NPC1RAB9ASCD5 | |
| SCHEMBL30630552 | 0.78 | ACACB (0.36) | ACACBMC4RMEN1ALDH1A1LMNA | |
| SCHEMBL24424352 | 0.78 | ACACB (0.36) | ACACBMC4RMEN1ALDH1A1LMNA | |
| SCHEMBL24423448 | 0.77 | MGLL (0.33) | NPC1RAB9AALDH1A1SMOMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |