Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29585253 | 1.00 | KDM5A (0.32) | KDM5AALDH1A1LRRK2HSD17B10MEN1 | |
| SCHEMBL24424757 | 0.91 | LRRK2 (0.36) | KDM5AALDH1A1LRRK2HSD17B10 | |
| SCHEMBL24424293 | 0.91 | LRRK2 (0.36) | KDM5AALDH1A1LRRK2HSD17B10 | |
| SCHEMBL24424456 | 0.91 | LRRK2 (0.36) | KDM5AALDH1A1LRRK2HSD17B10 | |
| SCHEMBL24424720 | 0.89 | LRRK2 (0.32) | KDM5AALDH1A1LRRK2HSD17B10 | |
| SCHEMBL24424721 | 0.89 | LRRK2 (0.32) | KDM5AALDH1A1LRRK2HSD17B10 | |
| SCHEMBL24424718 | 0.89 | LRRK2 (0.32) | KDM5AALDH1A1LRRK2HSD17B10 | |
| SCHEMBL25090753 | 0.88 | KDM4E (0.33) | KDM5AALDH1A1LRRK2HSD17B10 | |
| SCHEMBL29584774 | 0.88 | KDM4E (0.33) | KDM5AALDH1A1LRRK2HSD17B10 | |
| SCHEMBL24424759 | 0.84 | SPR (0.35) | KDM5ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |