Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797792 | 0.87 | PDE3B (0.42) | PDE3BPDE3ANOS2KDM4ELMNA | |
| SCHEMBL8332978 | 0.82 | LOXL2 (0.36) | HSP90AA1 | |
| SCHEMBL29364887 | 0.80 | PDE3B (0.39) | PDE3BPDE3ANOS2KDM4ELMNA | |
| SCHEMBL18641591 | 0.80 | PDE3B (0.39) | PDE3BPDE3ANOS2KDM4ELMNA | |
| SCHEMBL7497070 | 0.80 | PDE3B (0.33) | PDE3BPDE3ANOS2 | |
| SCHEMBL28571987 | 0.76 | NOS2 (0.48) | PDE3BPDE3ANOS2KDM4ELMNA | |
| SCHEMBL19932224 | 0.74 | SLC6A2 (0.35) | — | |
| SCHEMBL31168157 | 0.73 | PDE3B (0.38) | PDE3BPDE3ANOS2KDM4EHSP90AA1 | |
| SCHEMBL294405 | 0.73 | PDE3B (0.38) | PDE3BPDE3ANOS2KDM4EHSP90AA1 | |
| SCHEMBL30850058 | 0.73 | PDE3B (0.35) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |