Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24425228 | 0.87 | LMNA (0.39) | LMNAKDM4EHSD17B10MAPTHPGD | |
| SCHEMBL24419812 | 0.82 | LMNA (0.40) | LMNAKDM4EHSD17B10MAPTHPGD | |
| SCHEMBL24419428 | 0.82 | LMNA (0.41) | LMNAKDM4EHSD17B10MAPTHPGD | |
| SCHEMBL24425215 | 0.82 | LMNA (0.44) | LMNAKDM4EHSD17B10MAPTHPGD | |
| SCHEMBL24408958 | 0.81 | LMNA (0.48) | LMNAKDM4EHSD17B10MAPTHPGD | |
| SCHEMBL24409133 | 0.81 | NR1H4 (0.44) | LMNAKDM4EHSD17B10MAPTHPGD | |
| SCHEMBL24425234 | 0.81 | CNR1 (0.42) | KDM4ENR1H4ALDH1A1FAAHGAA | |
| SCHEMBL24409337 | 0.80 | LMNA (0.49) | LMNAKDM4EHSD17B10MAPTHPGD | |
| SCHEMBL24408960 | 0.80 | CNR1 (0.43) | LMNAMAPTNR1H4ALDH1A1GAA | |
| SCHEMBL24409359 | 0.80 | CXCR1 (0.43) | LMNAKDM4EMAPTS1PR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096448-A1 | [(5-PHENYL-5-HETEROARYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | WO | disclosed |