SCHEMBL24409359

SCHEMBL24409359

CCOC(=O)COc1cc(-c2cc(F)ccc2F)n(C)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR1 P25024 1/20 0.43
CXCR2 P25025 1/20 0.43
LMNA P02545 1/20 0.40
ADORA2A P29274 2/20 0.40
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
S1PR1 P21453 1/20 0.38
ADORA2B P29275 2/20 0.38
ADORA1 P30542 2/20 0.38
POLB P06746 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GAA P10253 1/20 0.38
NLRP3 Q96P20 1/20 0.38
PKM P14618 1/20 0.38
MAPT P10636 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
MEN1 O00255 1/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24409054 0.91 CXCR1 (0.43) CXCR1CXCR2LMNAADORA2AALDH1A1
SCHEMBL24425097 0.88 CXCR1 (0.42) CXCR1CXCR2ADORA2AALDH1A1SMN1; SMN2
SCHEMBL24408993 0.88 CXCR1 (0.42) CXCR1CXCR2LMNAADORA2AALDH1A1
SCHEMBL24409164 0.87 ALDH1A1 (0.45) CXCR1CXCR2ALDH1A1SMN1; SMN2KDM4E
SCHEMBL24409110 0.86 CXCR1 (0.48) CXCR1CXCR2ADORA2AALDH1A1SMN1; SMN2
SCHEMBL24409204 0.86 PKM (0.52) ADORA2AALDH1A1ADORA2BADORA1PKM
SCHEMBL24409330 0.84 MAPT (0.42) CXCR1CXCR2LMNAALDH1A1SMN1; SMN2
SCHEMBL24425115 0.82 ADORA2B (0.41) CXCR1CXCR2LMNAADORA2AADORA2B
SCHEMBL27114140 0.82 KDM4E (0.40) CXCR1CXCR2ADORA2AALDH1A1SMN1; SMN2
SCHEMBL24408995 0.82 ALDH1A1 (0.43) CXCR1CXCR2LMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022096450-A1 USE OF [(1,5-DIPHENYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AND THEIR SALTS AND COMPOSITIONS CONTAINING THEM, FOR REDUCING PHYTOTOXIC EFFECTS OF AGROCHEMICALS, IN PARTICULAR OF HERBICIDES, IN USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 WO disclosed