Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | S100A9 | P06702 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24425770 | 0.85 | ALDH1A1 (0.41) | ALDH1A1NPSR1S100A9MAPTFKBP1A | |
| SCHEMBL16002843 | 0.84 | HTR1D (0.43) | HTR1DHTR1BHTR1AHTR2AHTR2C | |
| SCHEMBL18571252 | 0.82 | MAPT (0.43) | ALDH1A1NPSR1S100A9MAPTFKBP1A | |
| SCHEMBL8751233 | 0.82 | ALDH1A1 (0.46) | ALDH1A1NPSR1MAPTFKBP1ARAB9A | |
| SCHEMBL20335487 | 0.80 | ALDH1A1 (0.45) | ALDH1A1NPSR1MAPTFKBP1ARAB9A | |
| SCHEMBL14155032 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NPSR1MAPTFKBP1ARAB9A | |
| SCHEMBL7665056 | 0.76 | KDM4E (0.54) | ALDH1A1ALKBH5GAA | |
| SCHEMBL12107538 | 0.75 | CYP3A4 (0.54) | ALDH1A1NPSR1HTR2AMAPTKDM1A | |
| SCHEMBL5323045 | 0.74 | TAAR1 (0.51) | S100A9CYP3A4 | |
| SCHEMBL9046172 | 0.74 | GAA (0.48) | ALDH1A1ALKBH5GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332443-B2 | Derivatives of halo quinabactin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332443-B2 | Derivatives of halo quinabactin | HDHD5, HSF1, NQO2 | ALDH1A1 2607/4885NPSR1 1048/4885S100A9 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.