Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18313841 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CCR3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2954759 | 0.66 | SSTR5 (0.68) | CCR3DRD2KMT2AMEN1CYP3A4 | |
| SCHEMBL28591741 | 0.66 | HTR7 (0.64) | ALDH1A1HTR7HTR1ADRD2HTR6 | |
| SCHEMBL363351 | 0.65 | NPC1 (0.60) | ALDH1A1CCR3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16828026 | 0.65 | KMT2A (0.79) | CCR3KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL24267995 | 0.64 | GAA (0.56) | ALDH1A1CCR3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23462319 | 0.63 | NPC1 (0.55) | ALDH1A1CCR3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23462320 | 0.63 | NPC1 (0.55) | ALDH1A1CCR3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31188489 | 0.63 | NPC1 (0.56) | ALDH1A1CCR3HTR7HTR1ADRD2 | |
| SCHEMBL31188531 | 0.63 | NPC1 (0.56) | ALDH1A1CCR3HTR7HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307742-B1 | METHODS OF TREATING OR PREVENTING A PROTEOPATHY | USHER III INITIATIVE INC (US) | 2022-05-18 | — | — | EP | disclosed |