Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19891953 | 0.89 | BTK (0.47) | BTKLCK | |
| SCHEMBL19891944 | 0.87 | BTK (0.51) | BTKLCK | |
| SCHEMBL19876236 | 0.80 | BTK (0.55) | BTKLCK | |
| SCHEMBL19891971 | 0.80 | BTK (0.52) | BTKLCK | |
| SCHEMBL24426209 | 0.79 | BTK (0.56) | BTKLCK | |
| SCHEMBL22659808 | 0.75 | BTK (0.53) | BTKLCK | |
| SCHEMBL29533525 | 0.75 | BTK (0.53) | BTKLCK | |
| SCHEMBL25882639 | 0.71 | BTK (0.46) | BTKLCK | |
| SCHEMBL24802261 | 0.70 | BTK (0.43) | BTKLCK | |
| SCHEMBL30950500 | 0.70 | BTK (0.67) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500569-B1 | 2-OXO-IMIDAZOPYRIDINES AS REVERSIBLE BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-05-18 | — | — | EP | disclosed |