Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | FABP4 | P15090 | 13/20 | 0.58 |
| ▸ | FABP5 | Q01469 | 13/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | CHD1L | Q86WJ1 | 1/20 | 0.55 |
| ▸ | PARP9 | Q8IXQ6 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24426787 | 0.88 | ALDH1A1 (0.57) | ALDH1A1RAB9AMAPTHTTFABP4 | |
| SCHEMBL29403771 | 0.88 | ALDH1A1 (0.69) | ALDH1A1RAB9AMAPTHTTFABP4 | |
| SCHEMBL29403396 | 0.87 | ALDH1A1 (0.76) | ALDH1A1RAB9AMAPTHTTFABP4 | |
| SCHEMBL20340280 | 0.84 | ALDH1A1 (0.74) | ALDH1A1RAB9AMAPTHTTFABP4 | |
| SCHEMBL20339092 | 0.83 | ALDH1A1 (0.67) | ALDH1A1RAB9AMAPTHTTFABP4 | |
| SCHEMBL24426878 | 0.83 | KDM4E (0.64) | ALDH1A1RAB9AMAPTKDM4EHSD17B10 | |
| SCHEMBL20340345 | 0.83 | ALDH1A1 (0.67) | ALDH1A1RAB9AMAPTHTTFABP4 | |
| SCHEMBL20353975 | 0.83 | POLB (0.78) | ALDH1A1RAB9AMAPTHTTFABP4 | |
| SCHEMBL24598779 | 0.82 | ALDH1A1 (0.62) | ALDH1A1RAB9AMAPTHTTFABP4 | |
| SCHEMBL20353999 | 0.82 | ALDH1A1 (0.62) | ALDH1A1RAB9AMAPTHTTFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562818-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-05-18 | — | — | EP | disclosed |