Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 12/20 | 0.52 |
| ▸ | FABP5 | Q01469 | 12/20 | 0.52 |
| ▸ | CHD1L | Q86WJ1 | 1/20 | 0.51 |
| ▸ | PARP9 | Q8IXQ6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20353999 | 0.91 | ALDH1A1 (0.62) | ALDH1A1RAB9AMAPTHTTKDM4E | |
| SCHEMBL20340298 | 0.91 | ALDH1A1 (0.62) | ALDH1A1RAB9AMAPTHTTKDM4E | |
| SCHEMBL24598779 | 0.91 | ALDH1A1 (0.62) | ALDH1A1RAB9AMAPTHTTKDM4E | |
| SCHEMBL21577820 | 0.91 | ALDH1A1 (0.59) | ALDH1A1RAB9AMAPTHTTKDM4E | |
| SCHEMBL20344333 | 0.89 | ALDH1A1 (0.65) | ALDH1A1RAB9AMAPTHTTKDM4E | |
| SCHEMBL20353887 | 0.89 | ALDH1A1 (0.65) | ALDH1A1RAB9AMAPTHTTKDM4E | |
| SCHEMBL24426767 | 0.88 | ALDH1A1 (0.60) | ALDH1A1RAB9AMAPTHTTKDM4E | |
| SCHEMBL20340346 | 0.84 | ALDH1A1 (0.64) | ALDH1A1RAB9AMAPTHTTPOLB | |
| SCHEMBL24426732 | 0.83 | ALDH1A1 (0.73) | ALDH1A1RAB9AMAPTHTTKDM4E | |
| SCHEMBL29403771 | 0.83 | ALDH1A1 (0.69) | ALDH1A1RAB9AMAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114349-B | Thiophene derivatives as antiviral agents | 埃尼奥制药公司 | 2022-03-15 | — | — | CN | claimed |
| US-11807618-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2023-11-07 | — | — | US | disclosed |
| US-11807618-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2023-11-07 | — | — | US | disclosed |
| US-20220213053-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-07-07 | — | — | US | disclosed |
| US-11279683-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2022-03-22 | — | — | US | disclosed |
| CN-110114349-B | Thiophene derivatives as antiviral agents | 埃尼奥制药公司 | 2022-03-15 | — | — | CN | disclosed |
| US-20190352275-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2019-11-21 | — | — | US | disclosed |
| EP-3562818-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | Enyo Pharma (FR) | 2019-11-06 | — | — | EP | disclosed |
| WO-2018122317-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2018-07-05 | — | — | WO | disclosed |
| WO-2018122317-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2018-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213053-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | MAVS, EIF2AK2, IRF3 | ALDH1A1 3437/4885RAB9A 1661/4885MAPT 3934/4885 |
| US-11279683-B2 | Thiophene derivatives as antiviral agents | MAVS, EIF2AK2, IRF3 | ALDH1A1 1759/4885RAB9A 1653/4885MAPT 4150/4885 |
| US-20190352275-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | MAVS, EIF2AK2, IRF3 | ALDH1A1 1759/4885RAB9A 1653/4885MAPT 4150/4885 |
| US-11807618-B2 | Thiophene derivatives as antiviral agents | MAVS, EIF2AK2, IRF3 | ALDH1A1 3437/4885RAB9A 1661/4885MAPT 3934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.