⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17687746 | 0.64 | — | — | |
| SCHEMBL6760698 | 0.63 | — | — | |
| SCHEMBL24936238 | 0.62 | NPC1 (0.32) | — | |
| SCHEMBL12827565 | 0.61 | GRM5 (0.37) | — | |
| SCHEMBL17431387 | 0.61 | HSD17B10 (0.34) | — | |
| SCHEMBL19062996 | 0.60 | — | — | |
| SCHEMBL22461956 | 0.60 | — | — | |
| SCHEMBL16284079 | 0.60 | — | — | |
| SCHEMBL9368491 | 0.58 | L3MBTL1 (0.42) | — | |
| SCHEMBL21852363 | 0.57 | CDK8 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998107-A1 | METHOD FOR PRODUCING INSULIN-PRODUCING CELL USING DIHYDROINDOLIZINONE DERIVATIVES | Tokyo Institute of Technology (JP) | 2022-05-18 | — | — | EP | disclosed |