Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 6/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708506 | 0.83 | IKBKB (0.35) | CDK8CDK19IKBKBLIMK1ALDH1A1 | |
| SCHEMBL9368491 | 0.82 | L3MBTL1 (0.42) | ALDH1A1HPGDGAANPC1MEN1 | |
| SCHEMBL9643791 | 0.81 | NPC1 (0.35) | CDK8CDK19ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9643795 | 0.81 | L3MBTL1 (0.41) | ALDH1A1HPGDGAANPC1MEN1 | |
| SCHEMBL21771163 | 0.78 | NPC1 (0.52) | ALDH1A1HPGDHSD17B10GAALMNA | |
| SCHEMBL17483809 | 0.77 | CDK8 (0.40) | CDK8CDK19IKBKBLIMK1ALDH1A1 | |
| SCHEMBL1477812 | 0.75 | RAB9A (0.47) | CDK8IKBKBLIMK1ALDH1A1HPGD | |
| SCHEMBL21852323 | 0.74 | IKBKB (0.40) | CDK8CDK19IKBKBLIMK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5012066 | 0.74 | RAB9A (0.46) | CDK8IKBKBLIMK1ALDH1A1HPGD | |
| SCHEMBL12661728 | 0.74 | IKBKB (0.42) | CDK8CDK19IKBKBLIMK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919488-B1 | IMMUNOMODULATOR | HITGEN INC (CN) | 2025-08-27 | — | — | EP | disclosed |
| US-20250011339-A1 | STING AGONIST COMPOUNDS AND METHODS OF USE | MERSANA THERAPEUTICS, INC. | 2025-01-09 | — | — | US | disclosed |
| WO-2024220889-A1 | STING AGONIST COMPOUNDS AND CONJUGATES THEREOF | SEAGEN INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-113563313-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-114585623-A | Bis [ N- ((5-carbamoyl) -1H-benzo [ d ] imidazol-2-yl) pyrazole-5-carboxamide ] derivatives and related compounds as STING (interferon gene stimulator) agonists for the treatment of cancer | 梅尔莎纳医疗公司 | 2022-06-03 | — | — | CN | disclosed |
| US-20220119379-A1 | IMMUNOMODULATOR | HITGEN INC. (CN) | 2022-04-21 | — | — | US | disclosed |
| WO-2020156363-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2020-08-06 | — | — | WO | disclosed |
| EP-3628676-A1 | MODIFIED PEPTIDES AND THEIR USES | Université de Montpellier (FR) | 2020-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119379-A1 | IMMUNOMODULATOR | STING1, TLR9, CGAS | CDK8 3026/4885CDK19 2718/4885IKBKB 185/4885 |
| US-20250011339-A1 | STING AGONIST COMPOUNDS AND METHODS OF USE | STING1, IRF3, MAVS | CDK8 2521/4885CDK19 4404/4885IKBKB 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.