Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26684141 | 0.82 | CTSL (0.38) | KDM1AKCNH2KDM1B | |
| SCHEMBL30668100 | 0.82 | CTSL (0.38) | KDM1AKCNH2KDM1B | |
| SCHEMBL20136336 | 0.79 | CES2 (0.50) | — | |
| SCHEMBL20148151 | 0.79 | CES2 (0.50) | — | |
| SCHEMBL20136335 | 0.79 | CES2 (0.50) | — | |
| SCHEMBL18302377 | 0.78 | USP2 (0.43) | — | |
| SCHEMBL18502958 | 0.78 | USP2 (0.43) | — | |
| SCHEMBL18302376 | 0.78 | USP2 (0.43) | — | |
| SCHEMBL18302283 | 0.76 | HPGD (0.42) | — | |
| SCHEMBL18302281 | 0.76 | HPGD (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998263-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2022-05-18 | — | — | EP | disclosed |