Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22523926 | 0.85 | DRD2 (0.40) | DRD2DRD1GFERCHRNB2CHRNA4 | |
| SCHEMBL20356071 | 0.81 | KDM1A (0.46) | DRD2DRD1KDM1AHTR2C | |
| SCHEMBL13091074 | 0.78 | DRD2 (0.48) | DRD2DRD1GFERCHRNB2CHRNA4 | |
| SCHEMBL8285956 | 0.77 | DRD2 (0.47) | DRD2DRD1GFERCHRNB2CHRNA4 | |
| SCHEMBL25563931 | 0.77 | CHRNB2 (0.38) | DRD2DRD1CHRNB2CHRNA4CA1 | |
| SCHEMBL12280032 | 0.76 | DRD2 (0.46) | DRD2DRD1GFERCHRNB2CHRNA4 | |
| SCHEMBL27670223 | 0.73 | DRD2 (0.43) | DRD2DRD1GFERCHRNB2CHRNA4 | |
| SCHEMBL13091371 | 0.72 | DRD2 (0.39) | DRD2DRD1GFERTRPM5KDM1A | |
| SCHEMBL27982634 | 0.72 | DRD2 (0.43) | DRD2DRD1GFERCHRNB2CHRNA4 | |
| SCHEMBL14395237 | 0.71 | CHRNB2 (0.44) | DRD2DRD1CHRNB2CHRNA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998263-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2022-05-18 | — | — | EP | disclosed |