SCHEMBL24429773

SCHEMBL24429773

BN(c1noc2cccc(C3CC3)c12)S(=O)(=O)c1cc(CC)ccc1OC

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 7/20 0.41
▸ KAT6A Q92794 7/20 0.41
▸ KAT6B Q8WYB5 6/20 0.41
▸ KAT5 Q92993 4/20 0.41
▸ KAT8 Q9H7Z6 4/20 0.41
▸ BRD4 O60885 2/20 0.38
▸ BRD2 P25440 2/20 0.38
▸ BRD3 Q15059 2/20 0.38
▸ MAPT P10636 3/20 0.36
▸ TP53 P04637 1/20 0.36
▸ ALPL P05186 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ KCNA5 P22460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24429771 0.87 KAT7 (0.42) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL29652415 0.83 KAT7 (0.37) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31605613 0.80 KAT6A (0.60) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21596870 0.80 KAT6A (0.60) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21660335 0.78 BRD4 (0.40) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21596865 0.76 KAT6A (0.57) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31605637 0.76 KAT6A (0.57) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21660533 0.76 POLB (0.41) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21609057 0.72 KAT6A (0.57) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL29652392 0.72 KAT7 (0.38) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT7 490/4885KAT6A 877/4885KAT6B 1005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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