SCHEMBL24433136

SCHEMBL24433136

c1ccc(-c2ncc(-c3c4ccccc4c(-c4ccc(-c5nc6ccccc6nc5-c5ccccc5)cc4)c4ccccc34)cn2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.49
KDM4E B2RXH2 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
GAA P10253 1/20 0.49
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 1/20 0.47
RECQL P46063 1/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
ATM Q13315 1/20 0.45
ALDH1A1 P00352 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
AKT1 P31749 1/20 0.43
AKT2 P31751 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1766036 0.87 L3MBTL1 (0.62) LMNAKDM4EL3MBTL1MEN1KMT2A
SCHEMBL22470183 0.87 L3MBTL1 (0.62) LMNAKDM4EL3MBTL1MEN1KMT2A
SCHEMBL13614893 0.85 L3MBTL1 (0.60) LMNAKDM4EL3MBTL1MEN1KMT2A
SCHEMBL24433253 0.84 LMNA (0.43) LMNAKDM4EL3MBTL1MEN1KMT2A
SCHEMBL24433135 0.83 LMNA (0.47) LMNAKDM4EL3MBTL1MEN1KMT2A
SCHEMBL22470166 0.83 LMNA (0.50) LMNAKDM4EL3MBTL1MEN1KMT2A
SCHEMBL24433131 0.82 TDP1 (0.54) LMNAKDM4EL3MBTL1MEN1KMT2A
SCHEMBL24433252 0.80 LMNA (0.47) LMNAKDM4EL3MBTL1MEN1KMT2A
SCHEMBL24433254 0.80 LMNA (0.47) LMNAKDM4EL3MBTL1MEN1KMT2A
SCHEMBL12262996 0.78 NPC1 (0.55) LMNAMEN1KMT2ATDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220158100-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220158100-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device NQO1, CYP1A1, CYBA LMNA 949/4885KDM4E 2917/4885L3MBTL1 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.