SCHEMBL24433161

SCHEMBL24433161

c1cncc(-c2c3ccccc3c(-c3ccc(-c4nc5ccccc5nc4-c4ccc5ccccc5c4)cc3)c3ccccc23)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 6/20 0.57
CYP11B2 P19099 6/20 0.57
CYP17A1 P05093 4/20 0.57
CYP19A1 P11511 3/20 0.57
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CYP2A6 P11509 1/20 0.47
CYP2C9 P11712 2/20 0.43
GRM1 Q13255 1/20 0.43
MAPK8 P45983 1/20 0.43
MAPK9 P45984 1/20 0.43
MAPK10 P53779 1/20 0.43
GBA1 P04062 1/20 0.42
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24433120 0.95 CYP11B1 (0.57) CYP11B1CYP11B2CYP17A1CYP19A1NPC1
SCHEMBL24433101 0.93 CYP11B1 (0.51) CYP11B1CYP11B2CYP17A1CYP19A1NPC1
SCHEMBL24433107 0.90 CYP11B2 (0.57) CYP11B1CYP11B2CYP17A1CYP19A1CYP2A6
SCHEMBL29412315 0.89 LMNA (0.49) CYP11B1CYP2C9MAPK10CYP1A2CYP3A4
SCHEMBL22470522 0.89 LMNA (0.49) CYP11B1CYP2C9MAPK10CYP1A2CYP3A4
SCHEMBL24433102 0.88 DHODH (0.48) CYP11B1CYP19A1NPC1RAB9ACYP2C9
SCHEMBL24433155 0.88 DHODH (0.48) CYP11B1CYP19A1NPC1RAB9ACYP2C9
SCHEMBL13727468 0.88 CYP11B2 (0.71) CYP11B1CYP11B2CYP17A1CYP19A1NPC1
SCHEMBL13146179 0.86 CYP11B1 (0.72) CYP11B1CYP11B2CYP17A1CYP19A1NPC1
SCHEMBL24433153 0.85 CYP11B1 (0.48) CYP11B1CYP19A1CYP2A6CYP2C9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220158100-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220158100-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device NQO1, CYP1A1, CYBA CYP11B1 585/4885CYP11B2 669/4885CYP17A1 2644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.