Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965867 | 0.85 | TSHR (0.38) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL22340222 | 0.83 | TSHR (0.41) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL24433234 | 0.81 | ALDH1A1 (0.36) | TSHRALDH1A1KMT2AMEN1CTSS | |
| SCHEMBL15159952 | 0.74 | TSHR (0.48) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL24490937 | 0.71 | — | — | |
| SCHEMBL3225387 | 0.70 | TSHR (0.43) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL491197 | 0.70 | TSHR (0.43) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL15355937 | 0.69 | TSHR (0.41) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL18155288 | 0.68 | TSHR (0.52) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL6762562 | 0.68 | TSHR (0.55) | TSHRL3MBTL1LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220154271-A1 | COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-05-19 | — | — | US | disclosed |