Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 14/20 | 0.62 |
| ▸ | ATP4B | P51164 | 14/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2380483 | 0.99 | ATP4A (0.63) | ATP4AATP4BABL1CYP1A1CYP1A2 | |
| SCHEMBL2379298 | 0.90 | ATP4A (0.59) | ATP4AATP4BABL1MEN1KMT2A | |
| SCHEMBL2490871 | 0.89 | ATP4A (0.68) | ATP4AATP4BMEN1KMT2A | |
| SCHEMBL2443736 | 0.87 | MEN1 (0.60) | ATP4AATP4BMEN1KMT2AALDH1A1 | |
| SCHEMBL2443681 | 0.87 | ATP4A (0.66) | ATP4AATP4BMEN1KMT2A | |
| SCHEMBL2443764 | 0.86 | ATP4A (0.60) | ATP4AATP4BRORC | |
| Bromide SCHEMBL2380198 | 0.86 | MEN1 (0.59) | ATP4AATP4BMEN1KMT2AALDH1A1 | |
| SCHEMBL2379141 | 0.86 | ATP4A (0.56) | ATP4AATP4B | |
| Bromide SCHEMBL2380835 | 0.86 | ATP4A (0.67) | ATP4AATP4BMEN1KMT2A | |
| Bromide SCHEMBL2382158 | 0.85 | ATP4A (0.61) | ATP4AATP4BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716127-B1 | GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBVIE DEUTSCHLAND (DE) | 2014-08-06 | — | — | EP | disclosed |
| EP-2380885-A1 | Guanidine compounds and use of same as binding partners for 5-HT5 receptors | Abbott GmbH & Co. KG (DE) | 2011-10-26 | — | — | EP | disclosed |
| EP-2366392-A1 | Guanidine compounds and use of same as binding partners for 5-HT5 receptors | Abbott GmbH & Co. KG (DE) | 2011-09-21 | — | — | EP | disclosed |
| EP-2366697-A1 | Guanidine compounds and use of same as binding partners for 5-HT5 receptors | Abbott GmbH & Co. KG (DE) | 2011-09-21 | — | — | EP | disclosed |