Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.51 |
| ▸ | ITGAV | P06756 | 9/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | LDLR | P01130 | 1/20 | 0.48 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 7/20 | 0.48 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.48 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22193945 | 1.00 | ITGB3 (0.51) | ITGB3ITGAVITGA2BHDAC3HDAC1 | |
| SCHEMBL22193994 | 1.00 | ITGB3 (0.51) | ITGB3ITGAVITGA2BHDAC3HDAC1 | |
| SCHEMBL22193877 | 1.00 | ITGB3 (0.51) | ITGB3ITGAVITGA2BHDAC3HDAC1 | |
| SCHEMBL18504802 | 0.94 | HDAC8 (0.46) | ITGB3ITGAVITGA2BHDAC3HDAC1 | |
| SCHEMBL18504798 | 0.94 | HDAC8 (0.46) | ITGB3ITGAVITGA2BHDAC3HDAC1 | |
| SCHEMBL16883967 | 0.90 | ITGB3 (0.49) | ITGB3ITGAVITGA2BHDAC3HDAC1 | |
| SCHEMBL16883952 | 0.90 | ITGB3 (0.49) | ITGB3ITGAVITGA2BHDAC3HDAC1 | |
| SCHEMBL22193974 | 0.88 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL16883990 | 0.88 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL16884024 | 0.88 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153812-A1 | INTEGRIN ANTAGONISTS | THE GENERAL HOSPITAL CORPORATION | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153812-A1 | INTEGRIN ANTAGONISTS | ITGB3, ITGA2B, ITGB1 | ITGB3 1/4885ITGAV 8/4885ITGA2B 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.