SCHEMBL24433797

SCHEMBL24433797

COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(NC(=O)COc5ccccc5)nc43)[C@@H](OCOCOCCC#N)[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TYMP P19971 10/20 0.42
TAS1R3 Q7RTX0 2/20 0.34
TAS1R1 Q7RTX1 2/20 0.34
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NT5E P21589 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25569964 1.00 TYMP (0.42) TYMPTAS1R3TAS1R1KDM4ENPC1
SCHEMBL24548715 1.00 TYMP (0.42) TYMPTAS1R3TAS1R1KDM4ENPC1
SCHEMBL22960797 0.98 TYMP (0.41) TYMPTAS1R3TAS1R1KDM4ENPC1
SCHEMBL12513080 0.94 TYMP (0.40) TYMPTAS1R3TAS1R1KDM4ENT5E
SCHEMBL15060564 0.92 TYMP (0.39) TYMPTAS1R3TAS1R1
SCHEMBL12434625 0.92 TYMP (0.39) TYMPTAS1R3TAS1R1
SCHEMBL11943227 0.91 TYMP (0.38) TYMPTAS1R3TAS1R1NT5E
SCHEMBL916676 0.91 TYMP (0.42) TYMPTAS1R3TAS1R1KDM4ENPC1
SCHEMBL16326506 0.89 TYMP (0.43) TYMPTAS1R3TAS1R1KDM4EHPGD
SCHEMBL6398167 0.88 TYMP (0.42) TYMPTAS1R3TAS1R1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322842-A1 COMPOSITION CONTAINING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-12 US disclosed
US-20230312635-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-05 US disclosed
US-20230256425-A1 INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-17 US disclosed
US-20230242570-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-03 US disclosed
US-20230167152-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-01 US disclosed
US-20220153774-A1 INORGANIC POROUS CARRIER AND METHOD FOR PRODUCING NUCLEIC ACIDS USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312635-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER POLRMT, RNGTT, POLM TYMP 88/4885TAS1R3 1150/4885TAS1R1 963/4885
US-20230256425-A1 INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD DNMT3L, FBL, SIK1 TYMP 184/4885TAS1R3 1440/4885TAS1R1 933/4885
US-20230167152-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER POLI, POLL, DNMT3A TYMP 1030/4885TAS1R3 2805/4885TAS1R1 2920/4885
US-20230322842-A1 COMPOSITION CONTAINING NUCLEIC ACID OLIGOMER NSUN2, RNGTT, NSUN3 TYMP 497/4885TAS1R3 1868/4885TAS1R1 998/4885
US-20220153774-A1 INORGANIC POROUS CARRIER AND METHOD FOR PRODUCING NUCLEIC ACIDS USING SAME SLCO2A1, SLCO2B1, SLCO4C1 TYMP 702/4885TAS1R3 1082/4885TAS1R1 619/4885
US-20230242570-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER FBL, POLI, POLL TYMP 689/4885TAS1R3 1306/4885TAS1R1 1304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.