SCHEMBL24433799

SCHEMBL24433799

COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(NC(C)=O)nc3=O)[C@@H](OCOCOCCC#N)[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.35
P2RY6 Q15077 3/20 0.32
P2RY14 Q15391 2/20 0.32
NT5E P21589 1/20 0.32
P2RY2 P41231 1/20 0.31
P2RY4 P51582 1/20 0.31
GAPDH P04406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26002238 1.00 TYMP (0.35) TYMPP2RY6P2RY14NT5EP2RY2
SCHEMBL22960854 0.98 TYMP (0.34) TYMPP2RY6P2RY14NT5EP2RY2
SCHEMBL13715722 0.95 TYMP (0.37) TYMPP2RY6P2RY14NT5EP2RY2
SCHEMBL3915198 0.95 TYMP (0.37) TYMPP2RY6P2RY14NT5EP2RY2
SCHEMBL16326505 0.94 TYMP (0.34) TYMPP2RY6P2RY14NT5EP2RY2
SCHEMBL6398949 0.94 TYMP (0.34) TYMPP2RY6P2RY14NT5EP2RY2
SCHEMBL667613 0.93 TYMP (0.37) TYMPP2RY6P2RY14NT5EP2RY2
SCHEMBL29195406 0.93 TYMP (0.37) TYMPP2RY6P2RY14NT5EP2RY2
SCHEMBL24878606 0.93 TYMP (0.37) TYMPP2RY6P2RY14NT5EP2RY2
SCHEMBL31229956 0.93 TYMP (0.37) TYMPP2RY6P2RY14NT5EP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312635-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-05 US disclosed
US-20230167152-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-01 US disclosed
US-20220177319-A1 INORGANIC POROUS SUPPORT AND METHOD FOR PRODUCING NUCLEIC ACID USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-06-09 US disclosed
US-20220153774-A1 INORGANIC POROUS CARRIER AND METHOD FOR PRODUCING NUCLEIC ACIDS USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312635-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER POLRMT, RNGTT, POLM TYMP 88/4885P2RY6 815/4885P2RY14 1455/4885
US-20230167152-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER POLI, POLL, DNMT3A TYMP 1030/4885P2RY6 1847/4885P2RY14 4051/4885
US-20220153774-A1 INORGANIC POROUS CARRIER AND METHOD FOR PRODUCING NUCLEIC ACIDS USING SAME SLCO2A1, SLCO2B1, SLCO4C1 TYMP 702/4885P2RY6 3740/4885P2RY14 3743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.