Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24434894 | 0.95 | SCN3A (0.45) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL24435435 | 0.88 | MEN1 (0.57) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL24435294 | 0.88 | SCN3A (0.47) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL24434828 | 0.86 | NPC1 (0.43) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL24435076 | 0.85 | MEN1 (0.48) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL24434983 | 0.83 | SMN1; SMN2 (0.44) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL24435033 | 0.81 | SMN1; SMN2 (0.42) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL24434680 | 0.81 | SMN1; SMN2 (0.42) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL24434845 | 0.80 | SMN1; SMN2 (0.45) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL24434537 | 0.80 | SMN1; SMN2 (0.60) | CYP1A2CYP2D6CYP2C9CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | CYP1A2 3277/4885CYP2D6 3197/4885CYP2C9 3349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.