Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24435174 | 1.00 | ROCK1 (0.49) | ROCK1SIGMAR1SCN3AMMP2MMP8 | |
| SCHEMBL24435404 | 0.96 | ROCK1 (0.46) | ROCK1SIGMAR1SCN3AMMP2MMP8 | |
| SCHEMBL24434863 | 0.90 | ROCK1 (0.40) | ROCK1SCN3AMMP2MMP8KDM4E | |
| SCHEMBL24434649 | 0.90 | ROCK1 (0.40) | ROCK1SCN3AMMP2MMP8KDM4E | |
| SCHEMBL24434786 | 0.88 | ADORA1 (0.47) | ROCK1SCN3AKDM4ESMN1; SMN2HTT | |
| SCHEMBL24435188 | 0.88 | TMIGD3 (0.41) | ROCK1SCN3AMMP2MMP8KDM4E | |
| SCHEMBL24435183 | 0.87 | ADORA1 (0.45) | ROCK1SCN3AKDM4ESMN1; SMN2HTT | |
| SCHEMBL24434676 | 0.87 | BTK (0.43) | ROCK1SCN3AMMP2MMP8KDM4E | |
| SCHEMBL24435045 | 0.86 | TMIGD3 (0.43) | ROCK1SCN3AKDM4ESMN1; SMN2HTT | |
| SCHEMBL24435193 | 0.86 | SCN3A (0.42) | ROCK1SCN3AMMP2MMP8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | ROCK1 2147/4885SIGMAR1 3889/4885SCN3A 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.