Acexamic Acid

Acexamic Acid

SCHEMBL24435

CC(=O)NCCCCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 1.00
MAPK1 P28482 2/20 0.73
KDM4E B2RXH2 1/20 0.73
HIF1A Q16665 1/20 0.73
PRMT1 Q99873 1/20 0.68
PAOX Q6QHF9 3/20 0.59
PLA2G2A P14555 1/20 0.56
TSHR P16473 2/20 0.55
LMNA P02545 1/20 0.55
NFKB1 P19838 1/20 0.55
PMP22 Q01453 1/20 0.55
FOLH1 Q04609 1/20 0.53
PLA2G4A P47712 1/20 0.52
EPHX2 P34913 6/20 0.51
ALDH1A1 P00352 1/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
GPR84 Q9NQS5 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4609043 1.00 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL11712278 1.00 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL27099106 1.00 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL7900131 1.00 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL8098661 1.00 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL19816833 1.00 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL11399083 1.00 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL1001209 1.00 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
SCHEMBL22199749 1.00 ADRA1A (1.00) ADRA1AMAPK1KDM4EHIF1APRMT1
Acexamic Acid SCHEMBL1649364 0.98 ADRA1A (0.96) ADRA1AMAPK1KDM4EHIF1APRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3933 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146216-A1 MULTI-USE HEAVY-DUTY CLEANING AND DEGREASING COMPOSITION IN A SOLID DOSE ECOLAB USA INC. (US) 2026-05-28 US claimed
US-12178205-B2 Systems and methods for storing and preserving implantable devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-12-31 US claimed
CN-118512401-A Lipid vesicle compositions with permeation enhancers 迪迪艾斯研究公司 2024-08-20 CN claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
EP-3611254-B1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF HEXAMETHYLENEDIAMINE GENOMATICA INC (US) 2023-07-05 EP claimed
CN-115590982-A Deacetylase self-sacrifice system and application thereof 湖南大学(CN) 2023-01-13 CN claimed
WO-2022236273-A1 SYSTEMS AND METHODS FOR STORING AND PRESERVING IMPLANTABLE DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-11-10 WO claimed
EP-2785358-B1 INSULIN-MIMETICS AS THERAPEUTIC ADJUNCTS FOR BONE REGENERATION UNIV RUTGERS (US) 2022-06-01 EP claimed
EP-3413844-B1 ALLOGRAFT TISSUE EXHIBITING ANTIMICROBIAL ACTIVITY AND METHOD FOR PRODUCING THE SAME UNIV RUTGERS (US) 2022-04-06 EP claimed
US-20220088271-A1 METHODS FOR PREPARING TISSUE GRAFTS WITH ANTIMICROBIAL PROPERTIES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-03-24 US claimed
EP-0214357-B1 NOVEL CHEMICAL COMPOUND HAVING ANTIMYCOTIC, CICATRIZING AND ANTIINFLAMMATORY ACTIVITY CHINOIN S.p.A. (IT) 1990-10-24 EP claimed
US-4960917-A FORMING ZINC SALT WITH HYDROXIDE; ANTIULCER AGENTS LABORATORIOS VINAS, S.A. (ES) 1990-10-02 US claimed
EP-0376113-A1 A process for the preparation of an acexamic acid derivative LABORATORIOS VINAS S.A. (ES) 1990-07-04 EP claimed
EP-0369088-A1 Use of zinc acexamate in the prophylaxis of gastropathy induced by non-steroidal anti-inflammatory drugs LABORATORIOS VINAS S.A. (ES) 1990-05-23 EP claimed
US-4921942-A Organometallic compounds STEPAN COMPANY (US) 1990-05-01 US claimed
US-4675422-A ALUMINUM COATINGS STEPAN COMPANY (US) 1987-06-23 US claimed
EP-0220934-A2 Aluminium carboxylates STEPAN COMPANY (US) 1987-05-06 EP claimed
US-4657923-A Econazole-acexamic acid addition compound having antimycotic, cicatrizing and antiinflammatory activity CHINOIN S.P.A. (IT) 1987-04-14 US claimed
EP-0214357-A1 Novel chemical compound having antimycotic, cicatrizing and antiinflammatory activity CHINOIN S.p.A. (IT) 1987-03-18 EP claimed
US-3974215-A Process for directly obtaining the calcium and magnesium salts of the N-acetyl-amino-6-hexanoic acid from acetyl-caprolactame CHOAY S.A. (FR) 1976-08-10 US claimed