Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.73 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.68 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609043 | 1.00 | ADRA1A (1.00) | ADRA1AMAPK1KDM4EHIF1APRMT1 | |
| SCHEMBL11712278 | 1.00 | ADRA1A (1.00) | ADRA1AMAPK1KDM4EHIF1APRMT1 | |
| SCHEMBL27099106 | 1.00 | ADRA1A (1.00) | ADRA1AMAPK1KDM4EHIF1APRMT1 | |
| SCHEMBL7900131 | 1.00 | ADRA1A (1.00) | ADRA1AMAPK1KDM4EHIF1APRMT1 | |
| SCHEMBL8098661 | 1.00 | ADRA1A (1.00) | ADRA1AMAPK1KDM4EHIF1APRMT1 | |
| SCHEMBL19816833 | 1.00 | ADRA1A (1.00) | ADRA1AMAPK1KDM4EHIF1APRMT1 | |
| SCHEMBL11399083 | 1.00 | ADRA1A (1.00) | ADRA1AMAPK1KDM4EHIF1APRMT1 | |
| Acexamic Acid SCHEMBL24435 | 1.00 | ADRA1A (1.00) | ADRA1AMAPK1KDM4EHIF1APRMT1 | |
| SCHEMBL22199749 | 1.00 | ADRA1A (1.00) | ADRA1AMAPK1KDM4EHIF1APRMT1 | |
| Acexamic Acid SCHEMBL1649364 | 0.98 | ADRA1A (0.96) | ADRA1AMAPK1KDM4EHIF1APRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665736-B1 | CORONA-LIKE (GUANIDYL)-OLIGOSACCHARIDIC DERIVATIVES AS CELL-PENETRATING ENHANCERS FOR INTRACELLULAR DELIVERY OF COLLOIDAL THERAPEUTIC SYSTEMS | UNIV PADOVA (IT) | 2015-09-16 | — | — | EP | claimed |
| EP-2665736-A1 | CORONA-LIKE (GUANIDYL)-OLIGOSACCHARIDIC DERIVATIVES AS CELL-PENETRATING ENHANCERS FOR INTRACELLULAR DELIVERY OF COLLOIDAL THERAPEUTIC SYSTEMS | Universita' Degli Studi Di Padova (IT) | 2013-11-27 | — | — | EP | claimed |
| WO-2012097876-A1 | CORONA-LIKE (GUANIDYL)-OLIGOSACCHARIDIC DERIVATIVES AS CELL-PENETRATING ENHANCERS FOR INTRACELLULAR DELIVERY OF COLLOIDAL THERAPEUTIC SYSTEMS | UNIVERSITA' DEGLI STUDI DI PADOVA (IT) | 2012-07-26 | — | — | WO | claimed |
| CN-118515578-A | Degradation method of polyamide polymer | 中国科学技术大学 | 2024-08-20 | — | — | CN | disclosed |
| US-10788499-B2 | Methods for assaying palmitoyl protein thioesterase 1 and tripeptidyl peptidase activity in dried blood spots for detection of neuronal ceroid lipofuscinoses in newborns | UNIVERSITY OF WASHINGTON (US) | 2020-09-29 | — | — | US | disclosed |
| EP-3568404-A1 | STAR-LIKE (GUANIDYL)X-OLIGOSACCHARIDIC COMPOUNDS AND CONJUGATES OR COMPLEXES THEREOF | Universita' Degli Studi Di Padova (IT) | 2019-11-20 | — | — | EP | disclosed |
| US-20180209989-A1 | METHODS FOR ASSAYING PALMITOYL PROTEIN THIOESTERASE 1 AND TRIPEPTIDYL PEPTIDASE ACTIVITY IN DRIED BLOOD SPOTS FOR DETECTION OF NEURONAL CEROID LIPOFUSCINOSES IN NEWBORNS | UNIVERSITY OF WASHINGTON (US) | 2018-07-26 | — | — | US | disclosed |
| US-20180209989-A1 | METHODS FOR ASSAYING PALMITOYL PROTEIN THIOESTERASE 1 AND TRIPEPTIDYL PEPTIDASE ACTIVITY IN DRIED BLOOD SPOTS FOR DETECTION OF NEURONAL CEROID LIPOFUSCINOSES IN NEWBORNS | UNIVERSITY OF WASHINGTON (US) | 2018-07-26 | — | — | US | disclosed |
| WO-2018130282-A1 | STAR-LIKE (GUANIDYL)X-OLIGOSACCHARIDIC COMPOUNDS AND CONJUGATES OR COMPLEXES THEREOF | UNIVERSITA' DEGLI STUDI DI PADOVA (IT) | 2018-07-19 | — | — | WO | disclosed |
| WO-2017011582-A1 | METHODS FOR ASSAYING PALMITOYL PROTEIN THIOESTERASE 1 AND TRIPERTIDYL PEPTIDASE ACTIVITY IN DRIED BLOOD SPOTS FOR DETECTION OF NEURONAL CEROID LIPOFUSCINOSES IN NEWBORNS | GELB MICHAEL H (US) | 2017-01-19 | — | — | WO | disclosed |
| US-9440988-B2 | Regulators of the hedgehog pathway, compositions and uses related thereto | JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2016-09-13 | — | — | US | disclosed |
| EP-2665736-A1 | CORONA-LIKE (GUANIDYL)-OLIGOSACCHARIDIC DERIVATIVES AS CELL-PENETRATING ENHANCERS FOR INTRACELLULAR DELIVERY OF COLLOIDAL THERAPEUTIC SYSTEMS | Universita' Degli Studi Di Padova (IT) | 2013-11-27 | — | — | EP | disclosed |
| WO-2012097876-A1 | CORONA-LIKE (GUANIDYL)-OLIGOSACCHARIDIC DERIVATIVES AS CELL-PENETRATING ENHANCERS FOR INTRACELLULAR DELIVERY OF COLLOIDAL THERAPEUTIC SYSTEMS | UNIVERSITA' DEGLI STUDI DI PADOVA (IT) | 2012-07-26 | — | — | WO | disclosed |
| US-20120135066-A1 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | BEACHY PHILIP A (US) | 2012-05-31 | — | — | US | disclosed |
| US-8163719-B2 | Regulators of the hedgehog pathway, compositions and uses related thereto | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110263519-A1 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2011-10-27 | — | — | US | disclosed |
| US-7868135-B2 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | BIOWEST THERAPEUTICS INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| EP-1656390-A2 | COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF | MIGENIX INC. (CA) | 2006-05-17 | — | — | EP | disclosed |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2005-07-14 | — | — | US | disclosed |
| WO-2005000878-A2 | COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF | MIGENIX INC. (CA) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135066-A1 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | SHH, GLI1, SMO | ADRA1A 4803/4885MAPK1 2370/4885KDM4E 1013/4885 |
| US-20180209989-A1 | METHODS FOR ASSAYING PALMITOYL PROTEIN THIOESTERASE 1 AND TRIPEPTIDYL PEPTIDASE ACTIVITY IN DRIED BLOOD SPOTS FOR DETECTION OF NEURONAL CEROID LIPOFUSCINOSES IN NEWBORNS | PPT1, TPP1, SPTLC1 | ADRA1A 4538/4885MAPK1 3988/4885KDM4E 4097/4885 |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | NRDC, NOD2, NGLY1 | ADRA1A 4748/4885MAPK1 4132/4885KDM4E 4472/4885 |
| US-20110263519-A1 | REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO | SHH, GLI1, SMO | ADRA1A 4803/4885MAPK1 2370/4885KDM4E 1013/4885 |
| US-10788499-B2 | Methods for assaying palmitoyl protein thioesterase 1 and tripeptidyl peptidase activity in dried blood spots for detection of neuronal ceroid lipofuscinoses in newborns | PPT1, TPP1, SPTLC1 | ADRA1A 4538/4885MAPK1 3988/4885KDM4E 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.