Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627369 | 0.86 | — | — | |
| Urea SCHEMBL2440792 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| SCHEMBL848235 | 0.76 | — | — | |
| Propene SCHEMBL28173463 | 0.76 | — | — | |
| Urea SCHEMBL9791646 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| SCHEMBL848234 | 0.76 | — | — | |
| SCHEMBL90556 | 0.76 | — | — | |
| Propane SCHEMBL28495593 | 0.75 | TDP1 (0.38) | ALDH1A1TSHRFGFR4TDP1 | |
| SCHEMBL15825639 | 0.75 | TSHR (0.32) | ALDH1A1TSHR | |
| SCHEMBL15825638 | 0.75 | TSHR (0.32) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367618-A1 | MICROSPHERES | Akzo Nobel N.V. (NL) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010072663-A1 | MICROSPHERES | AKZO NOBEL N.V. (NL) | 2010-07-01 | — | — | WO | disclosed |