Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9717608 | 0.85 | LMNA (0.37) | ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL1529276 | 0.84 | — | — | |
| SCHEMBL90556 | 0.80 | — | — | |
| Urea SCHEMBL9791646 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Urea SCHEMBL2443503 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methane SCHEMBL27388130 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL1071602 | 0.78 | — | — | |
| Charcoal, Activated SCHEMBL890032 | 0.78 | — | — | |
| Urea SCHEMBL11879610 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| SCHEMBL11057434 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440919-A | CROSSLINKED WITH RESONANCE FREE DI(ALKENE TERTIARY AMINE) CYCLIC COMPOUNDS | BAUSCH & LOMB INCORPORATED (US) | 1984-04-03 | — | — | US | claimed |
| US-4436887-A | CONTACT LENSES, OXYGEN PERMEABILITY | BAUSCH & LOMB INCORPORATED (US) | 1984-03-13 | — | — | US | claimed |
| EP-0079720-A2 | Low n-vinyl lactam content-based biomedical devices and process for preparation thereof | BAUSCH & LOMB INCORPORATED (US) | 1983-05-25 | — | — | EP | claimed |
| EP-0079721-A2 | N-vinyl lactam-based biomedical devices and process for preparation thereof | BAUSCH & LOMB INCORPORATED (US) | 1983-05-25 | — | — | EP | claimed |
| EP-2367618-A1 | MICROSPHERES | Akzo Nobel N.V. (NL) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010072663-A1 | MICROSPHERES | AKZO NOBEL N.V. (NL) | 2010-07-01 | — | — | WO | disclosed |
| US-4870145-A | Process for preparing polymeric beads | BAUSCH & LOMB INCORPORATED (US) | 1989-09-26 | — | — | US | disclosed |