SCHEMBL24436712

SCHEMBL24436712

CC(=O)c1ccc(O)cc1OC(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
KCNK3 O14649 3/20 0.40
KCNK9 Q9NPC2 3/20 0.40
PDK2 Q15119 1/20 0.40
PDK4 Q16654 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
HSD17B1 P14061 1/20 0.39
MAPT P10636 2/20 0.38
HTT P42858 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24436713 0.86 KCNK3 (0.43) ALDH1A1CYP3A4HPGDMAPK1CA12
SCHEMBL27051473 0.84 ESR1 (0.53) ALDH1A1HPGDCA12CA1CA2
SCHEMBL21842996 0.83 CA12 (0.57) ALDH1A1HPGDMAPK1CA12CA1
SCHEMBL18354033 0.83 ALDH1A1 (0.50) ALDH1A1HPGDKCNK3KCNK9L3MBTL1
SCHEMBL24436793 0.82 HSP90AB1 (0.56) ALDH1A1CYP3A4CA12CA1CA2
SCHEMBL15884073 0.81 MAOA (0.47) ALDH1A1KCNK3KCNK9L3MBTL1MAOB
SCHEMBL21487102 0.80 CA12 (0.60) ALDH1A1CA12CA1CA2CA7
SCHEMBL3552125 0.79 HCRTR1 (0.48) ALDH1A1CA12CA1CA2CA7
SCHEMBL21695849 0.78 ALDH1A1 (0.47) ALDH1A1CYP3A4HPGDMAPK1CA12
Isopeonol SCHEMBL29757918 0.78 MAOB (0.57) ALDH1A1CYP3A4HPGDMAPK1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001336-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE Shin-Etsu Chemical Co., Ltd. (JP) 2022-05-25 EP disclosed
US-20220157484-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed