SCHEMBL24436846

SCHEMBL24436846

COc1ccc(OC(F)(F)F)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
GAA P10253 2/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
TUBB4A P04350 2/20 0.45
TUBB P07437 2/20 0.45
TUBA3C P0DPH7 2/20 0.45
TUBA1B P68363 2/20 0.45
TUBA4A P68366 2/20 0.45
TUBB4B P68371 2/20 0.45
TUBB3 Q13509 2/20 0.45
TUBB2A Q13885 2/20 0.45
TUBB8 Q3ZCM7 2/20 0.45
TUBA3E Q6PEY2 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4513429 0.85 TUBB4A (0.53) ALDH1A1GAATUBB4ATUBBTUBA3C
SCHEMBL7687597 0.85 ALDH1A1 (0.47) ALDH1A1GAANPC1RAB9ACA12
SCHEMBL31193435 0.81 CA12 (0.65) ALDH1A1CA12CA1CA2CA7
SCHEMBL23484366 0.80 EPHX2 (0.40) ALDH1A1GAACA12CA1CA2
SCHEMBL581508 0.80 TUBB4A (0.63) ALDH1A1GAANPC1RAB9ACA12
SCHEMBL24436862 0.80 CYP3A4 (0.49) GAANPC1RAB9ACA12CA9
SCHEMBL16952355 0.79 CA12 (0.47) ALDH1A1GAANPC1RAB9ACA12
SCHEMBL30289783 0.79 CA12 (0.47) ALDH1A1NPC1RAB9ACA12CA1
SCHEMBL13785412 0.79 PDE2A (0.47) ALDH1A1GAANPC1RAB9ACA12
SCHEMBL263498 0.79 CA12 (0.47) ALDH1A1NPC1RAB9ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220157484-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed