Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.54 |
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24437274 | 0.96 | CNR1 (0.51) | CNR1CNR2P2RX7SLC22A12ALDH1A1 | |
| SCHEMBL24437315 | 0.89 | CNR1 (0.45) | CNR1CNR2SLC22A12 | |
| SCHEMBL24437134 | 0.88 | CNR1 (0.54) | CNR1CNR2P2RX7OPRM1OPRL1 | |
| SCHEMBL24437154 | 0.88 | DYRK1A (0.49) | CNR1CNR2 | |
| SCHEMBL24437195 | 0.88 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL24437138 | 0.87 | CNR1 (0.57) | CNR1CNR2P2RX7ALDH1A1 | |
| SCHEMBL24437198 | 0.85 | CFD (0.42) | CNR1CNR2SLC22A12 | |
| SCHEMBL24437323 | 0.84 | PDE6D (0.42) | CNR1CNR2 | |
| SCHEMBL24437163 | 0.84 | CNR1 (0.51) | CNR1CNR2SLC22A12 | |
| SCHEMBL24437316 | 0.83 | CNR1 (0.53) | CNR1CNR2P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153735-A1 | Orai Channel Inhibitors | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153735-A1 | Orai Channel Inhibitors | ORAI2, ORAI1, ORAI3 | CNR1 940/4885CNR2 745/4885P2RX7 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.