Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | HRAS | P01112 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011460 | 0.95 | P2RY12 (0.42) | P2RY12HDAC1HDAC2HDAC8RPS6KA3 | |
| SCHEMBL4015028 | 0.94 | P2RY12 (0.44) | P2RY12HDAC1HDAC2HDAC8RPS6KA3 | |
| SCHEMBL5004528 | 0.93 | P2RY12 (0.43) | P2RY12HDAC1HDAC2HDAC8RPS6KA3 | |
| SCHEMBL3417244 | 0.90 | HDAC1 (0.42) | P2RY12HDAC1HDAC2HDAC8MAPT | |
| SCHEMBL3934001 | 0.90 | HDAC1 (0.42) | P2RY12HDAC1HDAC2HDAC8MAPT | |
| SCHEMBL14072167 | 0.87 | RPS6KA3 (0.39) | P2RY12HDAC1HDAC2HDAC8RPS6KA3 | |
| SCHEMBL4019734 | 0.87 | HDAC1 (0.43) | P2RY12HDAC1HDAC2HDAC8MAPT | |
| SCHEMBL3417386 | 0.87 | ERBB2 (0.43) | P2RY12HDAC1HDAC2HDAC8MAPT | |
| SCHEMBL14441974 | 0.87 | ERBB2 (0.43) | P2RY12HDAC1HDAC2HDAC8MAPT | |
| SCHEMBL14072171 | 0.87 | P2RY12 (0.39) | P2RY12HDAC1HDAC2HDAC8RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153727-A1 | METHOD FOR PRODUCING PYRROLE-IMIDAZOLE (POLY)AMIDE | KANEKA CORPORATION (JP) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153727-A1 | METHOD FOR PRODUCING PYRROLE-IMIDAZOLE (POLY)AMIDE | DDC, PAM, AADAC | P2RY12 2025/4885HDAC1 686/4885HDAC2 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.