Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19059261 | 0.97 | KCNH2 (0.52) | HPGDKDM4EL3MBTL1KCNH2GPR119 | |
| SCHEMBL19059471 | 0.82 | KCNH2 (0.45) | L3MBTL1KCNH2GPR119KMT2AFKBP1A | |
| SCHEMBL13195634 | 0.81 | KCNH2 (0.42) | KCNH2GPR119KMT2A | |
| SCHEMBL13195630 | 0.79 | DPP4 (0.52) | HPGDKDM4EKCNH2GPR119ALDH1A1 | |
| SCHEMBL19058661 | 0.79 | NAMPT (0.40) | KCNH2GPR119 | |
| SCHEMBL31481058 | 0.77 | PARP10 (0.47) | KDM4EALDH1A1 | |
| SCHEMBL13195638 | 0.77 | KCNH2 (0.39) | KCNH2GPR119KMT2A | |
| SCHEMBL19059479 | 0.77 | KMT2A (0.38) | KCNH2GPR119ALDH1A1KMT2AMAPT | |
| SCHEMBL19059291 | 0.77 | KMT2A (0.41) | L3MBTL1KCNH2GPR119RAB9AALDH1A1 | |
| SCHEMBL23226187 | 0.77 | GPR119 (0.42) | L3MBTL1KCNH2GPR119ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153719-A1 | GPR119 AGONISTS | KALLYOPE, INC. | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153719-A1 | GPR119 AGONISTS | GPR119, GLP1R, GCGR | HPGD 1594/4885KDM4E 1450/4885L3MBTL1 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.