Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13415330 | 1.00 | POLB (0.36) | POLBCYP1A2GAAPLK1CSNK2A1 | |
| SCHEMBL24438561 | 1.00 | POLB (0.36) | POLBCYP1A2GAAPLK1CSNK2A1 | |
| SCHEMBL14963603 | 1.00 | POLB (0.36) | POLBCYP1A2GAAPLK1CSNK2A1 | |
| SCHEMBL13415345 | 0.98 | POLB (0.38) | POLBCYP1A2GAAPLK1CSNK2A1 | |
| SCHEMBL19038311 | 0.93 | — | — | |
| SCHEMBL19443230 | 0.82 | — | — | |
| SCHEMBL14887246 | 0.80 | — | — | |
| SCHEMBL17987654 | 0.80 | — | — | |
| SCHEMBL25777199 | 0.79 | NOS1 (0.31) | — | |
| SCHEMBL21011044 | 0.78 | TP53 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022101363-A1 | MODIFIED VIRAL PARTICLES FOR GENE THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2022-05-19 | — | — | WO | disclosed |