SCHEMBL13415345

SCHEMBL13415345

Cn1nnc2c1CCCC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.38
CYP1A2 P05177 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
PKM P14618 1/20 0.32
PLK1 P53350 1/20 0.31
CSNK2A1 P68400 1/20 0.31
PLK3 Q9H4B4 1/20 0.31
KDM4E B2RXH2 2/20 0.30
APAF1 O14727 1/20 0.30
NSD2 O96028 1/20 0.30
TP53 P04637 1/20 0.30
CASP3 P42574 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14963603 0.98 POLB (0.36) POLBCYP1A2GAAMAPTTDP1
SCHEMBL13415330 0.98 POLB (0.36) POLBCYP1A2GAAMAPTTDP1
SCHEMBL24438544 0.98 POLB (0.36) POLBCYP1A2GAAMAPTTDP1
SCHEMBL24438561 0.98 POLB (0.36) POLBCYP1A2GAAMAPTTDP1
SCHEMBL19038311 0.95
SCHEMBL19443230 0.84
SCHEMBL25777199 0.81 NOS1 (0.31)
SCHEMBL19576178 0.80
SCHEMBL21011044 0.80 TP53 (0.33) TP53
SCHEMBL22597998 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117778012-A Stripping liquid composition for IGZO substrate, preparation method thereof and semiconductor element 易安爱富科技有限公司 2024-03-29 CN disclosed
CN-117784538-A Stripping liquid composition for IGZO substrate, preparation method thereof and semiconductor device 易安爱富科技有限公司 2024-03-29 CN disclosed
EP-3694858-B1 BICYCLIC COMPOUNDS FOR USE AS RIP1 KINASE INHIBITORS HOFFMANN LA ROCHE (CH) 2023-01-11 EP disclosed
CN-115079523-A Stripping liquid composition and preparation method thereof 易安爱富科技有限公司 2022-09-20 CN disclosed
US-10683302-B2 Inhibitors of the menin-MLL interaction VITAE PHARMACEUTICALS, LLC (US) 2020-06-16 US disclosed
US-20190144459-A1 INHIBITORS OF THE MENIN-MLL INTERACTION VITAE PHARMACEUTICALS, LLC 2019-05-16 US disclosed
WO-2019072942-A1 BICYCLIC COMPOUNDS FOR USE AS RIP1 KINASE INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2019-04-18 WO disclosed
US-7687500-B2 Substituted oxetanes, method of making, and method of use thereof THE UNIVERSITY OF CONNECTICUT (US) 2010-03-30 US disclosed
US-7687500-B2 Substituted oxetanes, method of making, and method of use thereof THE UNIVERSITY OF CONNECTICUT (US) 2010-03-30 US disclosed
US-20080139566-A1 SUBSTITUTED OXETANES, METHOD OF MAKING, AND METHOD OF USE THEREOF HOWELL AMY R 2008-06-12 US disclosed
US-20080139566-A1 SUBSTITUTED OXETANES, METHOD OF MAKING, AND METHOD OF USE THEREOF HOWELL AMY R 2008-06-12 US disclosed
US-7351827-B2 Substituted oxetanes, method of making, and method of use thereof THE UNIVERSITY OF CONNECTICUT (US) 2008-04-01 US disclosed
US-7351827-B2 Substituted oxetanes, method of making, and method of use thereof THE UNIVERSITY OF CONNECTICUT (US) 2008-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139566-A1 SUBSTITUTED OXETANES, METHOD OF MAKING, AND METHOD OF USE THEREOF PNP, TYMP, DHPS POLB 532/4885CYP1A2 1263/4885GAA 872/4885
US-20190144459-A1 INHIBITORS OF THE MENIN-MLL INTERACTION MLLT1, MEN1, MLLT3 POLB 3348/4885CYP1A2 4596/4885GAA 4640/4885
US-10683302-B2 Inhibitors of the menin-MLL interaction MLLT1, MEN1, MLLT3 POLB 3348/4885CYP1A2 4596/4885GAA 4640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.