Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 11/20 | 0.77 |
| ▸ | TMPRSS4 | Q9NRS4 | 9/20 | 0.68 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.66 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.66 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | IKBKB | O14920 | 1/20 | 0.57 |
| ▸ | CHUK | O15111 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MYLK | Q15746 | 1/20 | 0.57 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29454776 | 0.88 | P2RX1 (1.00) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 | |
| SCHEMBL2169619 | 0.88 | P2RX1 (1.00) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 | |
| SCHEMBL24460146 | 0.85 | P2RX1 (0.74) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 | |
| SCHEMBL24438716 | 0.84 | P2RX1 (0.87) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 | |
| SCHEMBL30692659 | 0.84 | P2RX1 (0.87) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 | |
| SCHEMBL13997576 | 0.82 | P2RX1 (0.51) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 | |
| SCHEMBL23685650 | 0.82 | P2RX1 (0.82) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 | |
| SCHEMBL13812666 | 0.82 | P2RX1 (0.82) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 | |
| SCHEMBL11683279 | 0.82 | P2RX1 (0.82) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 | |
| SCHEMBL17845883 | 0.82 | P2RX1 (0.82) | P2RX1TMPRSS4P2RX4P2RX7KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103572-A1 | COMPOUNDS AND METHODS OF INHIBITING BACTERIAL CHAPERONIN SYSTEMS | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-05-19 | — | — | WO | disclosed |