SCHEMBL2169619

SCHEMBL2169619

O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ P2RX1 P51575 11/20 1.00
▸ TMPRSS4 Q9NRS4 9/20 0.81
▸ P2RX4 Q99571 5/20 0.78
▸ P2RX7 Q99572 5/20 0.78
▸ KCNMA1 Q12791 3/20 0.77
▸ MEN1 O00255 1/20 0.66
▸ IKBKB O14920 1/20 0.66
▸ CHUK O15111 1/20 0.66
▸ KDR P35968 1/20 0.66
▸ FLT3 P36888 1/20 0.66
▸ KMT2A Q03164 1/20 0.66
▸ MYLK Q15746 1/20 0.66
▸ MAP4K5 Q9Y4K4 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454776 1.00 P2RX1 (1.00) P2RX1TMPRSS4P2RX4P2RX7KCNMA1
SCHEMBL24438716 0.93 P2RX1 (0.87) P2RX1TMPRSS4P2RX4P2RX7KCNMA1
SCHEMBL30692659 0.93 P2RX1 (0.87) P2RX1TMPRSS4P2RX4P2RX7KCNMA1
SCHEMBL24438051 0.91 P2RX1 (0.82) P2RX1TMPRSS4P2RX4P2RX7KCNMA1
SCHEMBL30692660 0.91 P2RX1 (0.82) P2RX1TMPRSS4P2RX4P2RX7KCNMA1
SCHEMBL23685650 0.90 P2RX1 (0.82) P2RX1TMPRSS4P2RX4P2RX7KCNMA1
SCHEMBL23675471 0.90 P2RX1 (0.82) P2RX1TMPRSS4P2RX4P2RX7KCNMA1
SCHEMBL13812666 0.90 P2RX1 (0.82) P2RX1TMPRSS4P2RX4P2RX7KCNMA1
SCHEMBL17845883 0.90 P2RX1 (0.82) P2RX1TMPRSS4P2RX4P2RX7KCNMA1
SCHEMBL24438815 0.90 P2RX1 (0.82) P2RX1TMPRSS4P2RX4P2RX7KCNMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240002332-A1 Small Molecule Inhibitors of SARS-CoV-2 Infections THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION 2024-01-04 — — US claimed
US-20200038350-A1 CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE DUKE UNIVERSITY 2020-02-06 — — US claimed
EP-3313388-A1 CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE Duke University (US) 2018-05-02 — — EP claimed
CN-105911162-B The assay method of bromo and Chlorosalicylic anilide in a kind of cosmetics 中国检验检疫科学研究院 2018-01-26 — — CN claimed
WO-2016210289-A1 CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE DUKE UNIVERSITY (US) 2016-12-29 — — WO claimed
CN-105911162-A Method for determining brominated and chlorinated salicylanilide in cosmetics 中国检验检疫科学研究院 2016-08-31 — — CN claimed
EP-3653303-B1 PIPETTE TIP RACK BIOTIX INC (US) 2025-02-26 — — EP disclosed
US-12201987-B2 Pipette tip rack BIOTIX, INC. (US) 2025-01-21 — — US disclosed
EP-4376673-B1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B V (NL) 2025-01-01 — — EP disclosed
CN-118042960-A Filaments for oral care implements 联合利华知识产权控股有限公司 2024-05-14 — — CN disclosed
US-20240002332-A1 Small Molecule Inhibitors of SARS-CoV-2 Infections THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION 2024-01-04 — — US disclosed
US-11793777-B2 Methods and compositions for treating conditions associated with an abnormal inflammatory response FIRST WAVE BIO, INC. (US) 2023-10-24 — — US disclosed
US-11793777-B2 Methods and compositions for treating conditions associated with an abnormal inflammatory response FIRST WAVE BIO, INC. (US) 2023-10-24 — — US disclosed
WO-2003049776-A1 ANTIMICROBIAL CONTACT LENS CASE NOVARTIS AG (CH) 2003-06-19 — — WO disclosed
US-20030108761-A1 Anti-bacterial paper products EDDLEMON TAMMY (US) 2003-06-12 — — US disclosed
US-6138315-A Antimicrobial active compounds CHESEBROUGH-POND'S USA CO., DIVISON OF CONOPCO, INC. (US) 2000-10-31 — — US disclosed
US-5919152-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1999-07-06 — — US disclosed
US-5846215-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-12-08 — — US disclosed
US-4022880-A ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS LEVER BROTHERS COMPANY (US) 1977-05-10 — — US disclosed
US-4010252-A POLYQUATERNARY AMMONIUM COMPOUND, DEODORANTS COLGATE-PALMOLIVE COMPANY (US) 1977-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002332-A1 Small Molecule Inhibitors of SARS-CoV-2 Infections ACE2, ACE, TMPRSS2 P2RX1 2669/4885TMPRSS4 14/4885P2RX4 3287/4885
US-20200038350-A1 CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE SFRP1, FZD7, WNT1 P2RX1 3423/4885TMPRSS4 2074/4885P2RX4 3784/4885
US-11793777-B2 Methods and compositions for treating conditions associated with an abnormal inflammatory response FH, CS, ECHS1 P2RX1 910/4885TMPRSS4 2067/4885P2RX4 694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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